Kansas City Chiefs vs. Indianapolis Colts
Chiefs RB Jamaal Charles isn't quite the feature back in Kansas City -- that's Thomas Jones -- but he is having a solid season himself.
Look for Charles to have an excellent day against the 29th ranked Colts rush defense.
Charles will be playing in that dome which will only make him faster. The Colts are built on speed but not a lot of them have Jamaal Charles-like speed.
Prediction: 120 yards rushing, 30 yards receiving, 1 TD