Durant put up a double-double of 25 points and 13 rebounds while Ibaka poured in 25 points in addition to getting three blocks. The Thunder took a five-point lead into the fourth quarter before going on a 19-8 run and cruising the rest of the way.
The Pistons remain winless on the season despite getting double-figure scoring from five different players, including 22 points on 8 for 10 shooting off the bench from rookie Andre Drummond. Tayshaun Prince added 16 points and Greg Monroe notched a double-double with 14 points and 10 rebounds as the Pistons fell to 0-6.
The Thunder got 32 points off the bench with all but three coming from backup guards Eric Maynor (13 points) and Kevin Martin (16 points). The Thunder shot 53.5 percent from the field, 40 percent from three and 80.8 percent from the free throw line.
The win moves the Thunder to 4-2 overall.