Oklahoma vs. Iowa State 2012: TV schedule, game time, spread and more

Can Oklahoma shake off its big loss to Notre Dame last week? They'll get their first chance this Saturday at Iowa State when the Sooners take on the Cyclones.

The No. 12 Sooners (5-2 overall, 3-1 Big 12) may not be national title contenders any longer, but they are still in the Big 12 championship picture. Against the Cyclones, Oklahoma will need a stronger defensive effort than they gave against the Fighting Irish. The Sooners allowed Notre Dame to rack up 215 yards on the ground and 20 fourth-quarter points. They'll also need to find their own ground game; Oklahoma managed just 15 rushing yards rushing last Saturday, undoing all the good Landry Jones did in the air with 356 yards passing.

Iowa State (5-3, 2-3) can play spoiler in the conference with a win over Oklahoma. The Cyclones snapped a two-game skid with a 35-21 win over winless Baylor. The game was a shootout, with the teams combining for more than 1,100 yards of offense, as Cyclones quarterback Steele Jantz tossed five scores to go with 381 yards. Iowa State will be taking the field without linebacker and defensive leader Jake Knott, however, who is out for the year with a shoulder injury.

Oddsmakers expect a high-scoring game, with an over/under of 52.5 points, but the spread is comfortably in Oklahoma's favor, with the Sooners as 11.5-point favorites.

Oklahoma and Iowa State will take the field at Jack Trice Stadium at 11 a.m. CT on Nov. 3. The game will be broadcast on ABC.