Chiefs RB Thomas Jones has been getting the majority of the carries in Kansas City to this point but I see that changing against the Colts.
Playing in that dome, on that turf...it doesn't make sense to run Jones more there. He has a physical brand of football that relies on picking up 4-5 yards at a time.
Charles is more suited for a game like this.
Prediction: 50 yards rushing, 0 TD