Week 5 NFL picks start with the Kansas City Chiefs and Indianapolis Colts.
Pete Prisco of CBS Sports picks the Colts by 16.
The Chiefs are coming off a bye, which means they've had two weeks to prepare for Peyton Manning. Defensive coordinator Romeo Crennel knows him well from being New England's DC during the glory days of the Pats-Colts rivalry. But the Colts played well in their lone home game, and they will be focused here after losing at Jacksonville. They win big. The Chiefs are exposed some.
The line on the game is eight points, which seems slightly high to me. I think with the way the Chiefs have been playing this won't be a blowout. I'm not ready to pick the Chiefs to win at this point but I don't think it'll be a blowout.