While ESPN's experts have picked the Chiefs over the Bills, the experts at CBS seem to prefer Buffalo. Seven of the nine experts at CBS think the Bills will prevail, with only Jason La Canorfa and Ryan Wilson picking the Chiefs to come out on top.
Pete Prisco had the following to say about his prediction that the Bills would prevail 27-21:
This a game matching two teams that had their high expectations smashed in a big way in their openers. Who regroups here? The Chiefs are on the road against a team playing its home opener after a loss. The Buffalo front didn't do much against the Jets. They do here. The Bills get after Matt Cassel and take it.
OddsShark has the Bills currently favored by a field goal. The game is scheduled to kick off at 12 p.m. CT from Ralph Wilson Stadium in Orchard Park, N.Y. It can be seen on CBS.
Sound off on who you think will win for each team by clicking on Arrowhead Pride for the Chiefs or Buffalo Rumblings for the Bills. You can check out SB Nation's total league coverage by reading its NFL Hub.