Alabama opened as a 17 1/2 point favorite for the first SEC contest ever between the two teams. Alabama has won both of its SEC games this season. Missouri is 0-3 in conference play, losing by large margins to South Carolina and Georgia before falling to Vanderbilt 19-15 this past Saturday.
Alabama's offense is averaging 401 yards per game and 40.1 points per game. Missouri's defense has allowed 22.8 ppg and 326.7 yards per game.
The Alabama defense ranks first in the nation in points against; opponents are averaging seven per game. The Missouri offense is averaging 25.3 ppg.
Alabama and Missouri have not played since 1978; the Tigers hold a 2-1 advantage in the all-time series. Most books have this game's over-under between 43 and 44.
Find all your updated NCAA football odds at the SBNation odds page.